Bathinapatla, AyyappaKanchi, SuvardhanSingh, ParveshSabela, Myalowenkosi InnocentBisetty, Krishna2016-06-232016-06-232015Bathinapatla, A;. Kanchi, S;. Singh, P;. Sabela, M. I. 2015. Fabrication of copper nanoparticles decorated multiwalled carbon nanotubes as a high performance electrochemical sensor for the detection of neotame. Biosensors and Bioelectronics Vol. 67 : 200–2070956-5663http://hdl.handle.net/10321/1566A highly sensitive and novel electrochemical sensor for the detection of neotame using differential pulse voltammetry with a modified glassy carbon electrode is presented. The method was further customized by the fabrication of the electrode surface with copper nanoparticles–ammonium piperidine dithiocar-bamate–mutiwalled carbon nanotubes assimilated with β-cyclodextrin. The multiwalled carbon nano-tubes assimilated with β-cyclodextrin/glassy carbon electrode exhibited catalytic activity towards the oxidation of neotame at a potential of 1.3 V at pH 3.0. The transmission electron microscopy, thermogravimetric analysis, frontier transform infrared spectroscopy and cyclic voltammetry were employed to characterize the electrochemical sensor. The sensitivity and detection limits of the electrode increased two-fold in contrast to the β-CD-MWCNTs/GCE sensor. The developed method was successfully applied for the determination of neotame in food samples, with results similar to those achieved by our modified capillary electrophoresis method with a 96% confidence level.8 penNeotameElectrochemical sensorCyclic voltammetryDifferential pulse voltammetryArticlehttps://doi.org/10.1016/j.bios.2014.08.017