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Research Publications (Health Sciences)

Permanent URI for this collectionhttp://ir-dev.dut.ac.za/handle/10321/216

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    Stakeholder knowledge and attitudes toward the use of predictive genetic testing in South Africa
    (Springer Science and Business Media LLC, 2022-12) Naidoo, Levani; Reddy, Poovendhree
    The use of predictive genetic testing, particularly for risk profiling in non-communicable diseases (NCDs), has the potential to benefit public health by decreasing the disease burden and alleviating the pressure on healthcare. It is thus important to assess knowledge and uptake among stakeholders. This study aimed to assess end users' (community, medical practitioners and medical students) knowledge and attitudes regarding the use and support of genomic medicine. A descriptive cross-sectional survey was conducted in Kwazulu-Natal (KZN) among 3 groups of stakeholders (n = 170): medical practitioners from both private and public healthcare, medical students from UKZN and community members represented by teachers. Three structured questionnaires using a Likert scale were administered. Responses were stratified by practice type, and a scoring scale was developed. Principal component analysis (PCA) was used to reduce data on all constructs that made up each variable. All three groups showed adequate knowledge and a positive attitude towards use, apart from medical students who were not as keen to support future use in their own practice. Although medical practitioners supported the use of this technology, with necessary guidelines, expertise and affordability, only 18% from private practice reported having used it. PCA reduced data to fewer parsimonious constructs for all 3 groups: common threads included an awareness that genetic testing may improve health and disease outcomes; guidelines for use; and the provision of education to increase awareness, training to bolster expertise and confidence to use these services. Participants in this study attributed a lack of uptake to limited expertise and professional support, and a lack of legislative guidelines. We recommend updating continuing professional development for medical practitioners and promoting community education concomitantly. Provision of guidelines and increased accessibility to resources are important.
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    A desktop evaluation of the potential impact of nanotechnology applications in the field of environmental health in a developing country
    (Science and Education Publishing, 2015) Naidoo, Levani; Kistnasamy, Emilie Joy
    Nanotechnology is the latest addition to enhancing lifestyles of the human population. It also has an impact on the core parts that are vital to the well-being of humanity and its’ sustainability. Nanotechnology has been researched and is implemented in a number of countries at a commercialized level. However, in South Africa, nanotechnology is still being explored at grassroots with a few private industries implementing it. Based on research, the public health sector is expected to benefit the most from the application of nanotechnology. An environmental health practitioner plays a key role in ensuring the health and sustainability of the human population. The purpose of this desktop study is to generally explore the uses of nanotechnology in the Public Health sector with specificity to food, health and water remediation in the context of environmental health in South Africa and evaluate the possible impacts nanotechnology will have in the South African society. Proposed recommendations to be considered on how to address the use of nanotechnology in the current state of South Africa are made along with identifying the gaps in research in nanotechnology pertaining to South Africa.