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Theses and dissertations (Health Sciences)

Permanent URI for this collectionhttp://ir-dev.dut.ac.za/handle/10321/12

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Has files: YesSubject: search.filters.subject.Osteoarthritis

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    A systematic review on the effectiveness of manipulation and mobilisation in the treatment of osteoarthritis
    (2023-05-31) Khamissa, Ahmed; Korporaal, Charmaine Maria
    Osteoarthritis (OA) is an increasing condition globally as the population ages and the number of elderly increases. However, there is a lack of relevant evidence-based guidelines for manual therapy in the treatment of OA especially involving OA of the spine, wrist, temporomandibular joint (TMJ), and the glenohumeral joint (GHJ). A systematic review organises and critiques literature in a more concise form for practitioners. This study aimed to briefly provide practitioners the evidence available on the effectiveness of manipulation and mobilisation on OA. Methods: A systematic review of available literature was performed using keywords including “manipulation”; “mobilization”; “manual therapy” and “osteoarthritis”; “spondylosis”; “degenerative joint disease”; “degenerative disc disease”. The database searches were through CINAHL, DUT summons, Google scholar, Pubmed and Scopus. Following a screening using inclusion criteria, 20 articles were chosen for review. Each of the studies were than reviewed by three reviewers using the Newcastle-Ottawa scale, the PEDRO scale, the Joanna Briggs Institute (JBI) scale for case series and the JBI scale for case reports. These scales evaluated the methodological rigour (internal validity) of the chosen articles. In addition, the external validity was determined through a critique of each article. The internal and external validity formed the basis for decisions on the level of evidence provided in support of manual therapy. Results: Of those chosen articles, 13 provided evidence of treatment programmes and could not contribute to evidence specific to mobilisation and manipulation. In contrast, four articles assessed the efficacy of mobilisation, one study assessed the efficacy of manipulation, and two studies assessed the efficacy of neural mobilisation. There was moderate evidence in support of mobilisation on thumb carpometacarpal (CMC) OA, but only limited evidence in support of its use on cervical spine OA and no evidence in support of its use on lumbar spine OA, GHJ OA and TMJ OA. Manipulation was suggested to have moderate to limited evidence in support of its use on lumbar spine OA, but no evidence for cervical spine OA. Neural mobilisation was suggested to have limited evidence in support of its use for treating thumb CMC OA. Conclusion: It was evident in this systematic review that there is limited evidence for mobilisation, manipulation and neural mobilisation. Further research is required to expand on the limited areas, as well as strengthen the current evidence for clinical use.
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    The efficacy of action potential therapy, transcutaneous electrical nerve stimulation and placebo in the treatment of osteoarthritis of the knee
    (2001) Naidoo, Seelan Sadasivasan Kisten; Myburgh, Cornelius
    Osteoarthritis (OA) is a disease that is localized to diarthodal joints and is characterized by degeneration of hyaline cartilage, with secondary changes in the peri-articular bone and soft tissue. OA is considered to be a sequale of traumatic and age respondent degenerative changes which result in loss of cartilage and impairment of function. The purpose of this investigation is to evaluate the relative efficacy of Action Potential Therapy, Transcutaneous Electrical Nerve Stimulation and placebo in the treatment of Osteoarthritis of the knee. This was a prospective, randomized clinical trial consisting of sixty patients who volunteered from the greater Durban area. The patients diagnosed as having Osteoarthritis of the knee, were randomly divided into four treatment groups. Group one and two consisted of twenty patients each and group three and four consisted often patients each, all between the age of 40 - 65 years old. Group one received Action Potential therapy (APT); group two received Transcutaneous Electrical Nerve Stimulation (TENS); group three received placebo APT and group four received placebo TENS. For statistical analysis parametric and non-parametric tests were used in all hypothesis Data capturing took place for all groups at the 1st, 2nd and 4th consultations. Subjective data was collected using the Numerical Pain Rating Scale-l Ol ; McGill Pain Questionaire and Western Ontario and MacMaster Universities Index (WOMAC). Objective data was gathered using the algometer and goniometer.