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Theses and dissertations (Health Sciences)

Permanent URI for this collectionhttp://ir-dev.dut.ac.za/handle/10321/12

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    An evaluation of 99mTc-MIBI imaging of Kaposi's Sarcoma in AIDS patients
    (2006) Peer, Fawzia Ismail
    The purpose of this study was to evaluate 99mTc- methoxyisobutylisonitrile (MIBI) imaging, in terms of sensitivity and specificity, for non invasively detecting extracutaneous involvement of Kaposi’s sarcoma (KS) and for differentiating pulmonary infection from malignancy in acquired immunodeficiency syndrome (AIDS) patients before and after treatment. Current investigations are invasive.
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    An evaluation of computerised tomography (CT) based treatment planning versus digitised image planning (standard planning technique) for carcinoma of the breast, using the four field breast technique
    (2007) Govender, Yoguvathie
    Aim/research questions The aim of the study was to evaluate CT-based treatment planning versus digitised image planning (standard planning technique) for carcinoma of the breast, using the four-field breast technique, in terms of the depth of supraclavicular and axillary nodes, the variability of the breast tissue and the dose inhomogeneity at the matchline. The variability of the depth of supraclavicular and axillary nodes has not been documented in any local or national studies. When simulating patients for treatment, it is evident that the anatomical variability of patient chest wall thickness, shape and size is a contributing factor towards the final treatment plan and dose distribution achieved. Therefore knowing the correct depth of the nodes and being able to clearly demarcate the breast tissue should result in a favourable dose administration. The following questions were addressed:  What is the dose to the supraclavicular nodes from both plans?  What is the dose to the axillary nodes from both plans?  How do the plans differ in terms of dose coverage to the supraclavicular and axillary nodes?  What is the relationship between the depth of the supraclavicular nodes and the patient separation? ii  What is the relationship between the depth of the axillary nodes and the patient separation?  Does the target volume receive adequate dose coverage from the plans?  How is dose to the heart volume affected by target coverage on both plans?  How is dose to the lung volume affected by target coverage on both plans?  What is the dose variability along the matchline?  Are the plans over dosing?  Are the plans under dosing?
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    A quantitative analysis of ionising radiation exposure to the hands, thyroid and whole body of orthopaedic registrars at King Edward VIII Hospital during fluoroscopic internal fixation of the lower limbs
    (2005) Abu Shab, Khaled M.
    The portable C-arm image intensifier has been of great value to orthopaedic registrars for many years. One of its common uses in trauma surgery is during controlled reduction of long bone fractures and accurate placement of internal or external fixation devices. Ionising radiation has therefore become a serious occupational hazard for the orthopaedic registrar. A prospective study was conducted in order to quantify the amount of ionising radiation exposure to the hands, thyroid and whole body of orthopaedic registrars during fluoroscopic internal fixation of the lower limbs, and to determine whether these registrars need to be routinely monitored for radiation exposure. The study also quantified the average operative and screening times for internal fixation of the lower limbs. The study provided information regarding the maximum number of internal fixations of the lower limbs that can be performed by the orthopaedic registrar before the maximum dose level to the hands is exceeded.