Research Publications (Applied Sciences)
Permanent URI for this collectionhttp://ir-dev.dut.ac.za/handle/10321/213
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Item 4-Dihydroxy-3-(indol-2-)-yl-quinoline via substantial methodology-fisher indole synthesis(Heterocyclic Letters, 2016) Pitchai, P.; Nepolraj, A.; Sathiyaseelan, M.; Gengan, Robert MoonsamyFisher indole methodology, a simple application was used to generate indole as a substitution on the quinoline ring. Conventional heating and microwave irradiation was compared. The ease of work up procedure, reduced time and moreover the high yield is exceptional however microwave irradiation presented more advantages.Item A one pot microwave assisted synthesis of 3-acyl-2,4-dihydroxyquinoline followed by synthesis of 7-methyldibenzo[c,f][2,7]naphthyridin-6(5H)-ones via three routes(NISCAIR, 2013) Pitchai, P.; Uvarani, C.; Gengan, Robert Moonsamy; Mohan, P. S.An easy one pot microwave assisted synthesis of 3-acyl-2,4-dihydroxyquinoline from simple precursors followed by convenient synthesis of novel and potential HIV integrase inhibitors 7-methyldibenzo[c,f][2,7]naphthyridin-6(5H)-ones has been achieved through three different routes. Mild reaction conditions and good yields are obtained by applying microwave and photochemical techniques.