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    Nano silver particles in biomedical and clinical applications : review
    (Oriental Scientific Pub Co, 2015-11) Krishna, Suresh Babu Naidu; Govender, Patrick; Adam, Jamila Khatoon
    Nanotechnology is most promising arena for generating new applications in medicine and advancing rapidly due to the great progress achieved in various fileds including electronics, machanics, cosmetics, food, etc. In order to successfully bifunctionalise nanoparticles for a given biomedical application, a wide range of chemical, physical and biological factors are to be taken into account. Silver nanoparticles (AgNPs) at nanoscale exhibits strong antibacterial activity vowing to their large surface to volume ratios and crystallographic surface structure. Nanosilver particles have been widely used in a range of biomedical applications including diagnosis, treatment, medical device coating, drug delivery and personal health care products. With the growing application of nanosilver particles in medical contexts, it is becoming necessary for a better understanding the mechanisms of action, biological interactions and their potential toxicity on exposure. This review aims to provide critical assessment of the current understanding of antibacterial activity, biomedical and clinical applications of silver nanoparticles.
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    The use of probiotics and safety concerns : a review
    (Academic Journals, 2012-10-27) Krishna, Suresh Babu Naidu; Adam, Jamila Khatoon; Govender, P.
    Probiotics are defined as “live microorganisms which when administered in adequate amounts confer a health benefit on the host’’. Most probiotics fall into the group of organisms’ known as lactic acid-producing bacteria and are normally consumed in the form of yogurt, fermented milks, cereal or other fermented foods. Many of the products currently available in the market are not clearly tied to research documenting beneficial effects. Probiotics are regulated by FDA and several reports are available now for mislabeling the product claiming health benefits. As live microbial products, probiotics are potential sources of risk and there exists skeptical attitude among medical professionals and consumers who have less than optimal experiences with probiotics. This review outlines information regarding probiotics, overview of proposed regulatory guidelines and commercial probiotic products available in the market considered as safe for humans.