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Antibiogram of environmental isolates of Acinetobacter calcoaceticus from Nkonkobe Municipality, South Africa
(PSP, 2016) Stenström, Thor-Axel; Okoh, Anthony I.; Adegoke, Anthony Ayodeji
The antibiogram of Acinetobacter isolates from freshwater and soil samples in Alice and Fort Beaufort towns in Nkonkobe Municipality, South Africa were assessed for their extended beta-lactamase (ESBL) spectrum. Eighty-six Acinetobacter isolates were obtained from the 50 samples of soil and 50 samples of water (25 in each location) analysed. The resistance of the Acinetobacter isolates ranged between 30-100% against penicillin G, ceftriazone, nitrofurantoin, erythromycin and augmentin, while 9% showed intermediate response to minocycline, and 10% were resistant to oxytetracycline. Both Tet B and Tet 39 were detected in 66.7 % of the tetracycline resistant Acinetobacter isolates and in 44.4 % of the intermediately tetracycline resistant Acinetobacter isolates. An observation of 9.3% phenotypic expression of ESBLs was made while 3.5% were carrying the blaCTX-M-1 gene; all of which were susceptible to the fluoroquinolone. The multiple antibiotic resistance (MAR) index of > 0.2 indicates that the isolates emerged from high-risk sources, in line with conventional standards. Commensal Acinetobacter spp in the environment have proven to be one of reservoirs for antibiotic resistance genes.