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Faculty of Applied Sciences

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    A novel alkaloid, four alkaloid precursors and a coumarin from Feronia limonia
    (NISCAIR-CSIR, India, 2012-12) Pitchai, P.; Ulagi, R.; Mohan, P. S.; Gengan, Robert Moonsamy
    A new quinoline alkaloid has been isolated from the flowers of Feronia limonia along with four alkaloid precursors, one coumarin, a known steroid stigmasterol and p-coumaric acid. The structures of compounds have been elucidated on the basis of spectroscopic data and comparison with the literature.
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    A one pot microwave assisted synthesis of 3-acyl-2,4-dihydroxyquinoline followed by synthesis of 7-methyldibenzo[c,f][2,7]naphthyridin-6(5H)-ones via three routes
    (NISCAIR, 2013) Pitchai, P.; Uvarani, C.; Gengan, Robert Moonsamy; Mohan, P. S.
    An easy one pot microwave assisted synthesis of 3-acyl-2,4-dihydroxyquinoline from simple precursors followed by convenient synthesis of novel and potential HIV integrase inhibitors 7-methyldibenzo[c,f][2,7]naphthyridin-6(5H)-ones has been achieved through three different routes. Mild reaction conditions and good yields are obtained by applying microwave and photochemical techniques.
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    Derivatives of coumarins, cinnamic acid and tyramine from leaves of Limonia crenulata
    (Pharmascope, 2013) Pitchai, P.; Ulagi, R.; Mohan, P. S.; Gengan, Robert Moonsamy
    The present research was designed to isolate the Coumarins, Cinnamic acid and Tyramine from Leaves of Limonia crenulata . N - benzoyl tyramine and 2,4 - dihydroxy - 3 - methoxy cinnamic acid were isolated for the first time from the leaves of Limonia crenulata. Known compounds stigmasterol, daphnetin - 8 - methyl eth er and umbelliferone were also recovered by chromatographic separation techniques. Five compounds were isolated from the acetone extract of Limonia Crenulata and their structures were confirmed from spectral evidence and comparison with literature values. The compounds included derivatives of coumarins, cinnamic acid and tyramine.