Vilsmeier-Haack reaction : a manifest protocol to synthesise bisquinoline
Date
2016-04
Journal Title
Journal ISSN
Volume Title
Publisher
NISCAIR-CSIR, India
Abstract
Synthesis of bisquinolines from methyl anthranilate and ethyl acetoacetate is described. This synthesis has been accomplished in three steps. Vilsmeier-Haack reaction is used as a key tool to assemble bisquinoline. Microwave heating during each step of the reaction gives high yield of products in short reaction times.
Description
Keywords
Bisquinolines, Claisen condensation, Vilsmeier-Haack reaction, Schiff base
Citation
Makhanya, T.R. et al. 2016. Vilsmeier-Haack reaction : a manifest protocol to synthesise bisquinoline. Indian Journal of Chemistry. 55B: 517-521.
DOI
https://doi.org/10.1002/chin.201640169