Silica-sulfuric acid : novel, simple, efficient and reusable catalyst for hydration of nitrile to amide
Date
2016
Journal Title
Journal ISSN
Volume Title
Publisher
Asian Publication Corporation
Abstract
Silica-sulfuric acid efficiently catalyzes conversion of aliphatic, substituted aromatic and hetero aromatic nitriles to their corresponding amides in good to excellent yields under reflux condition. Products obtained were purified by column chromatography method and characterized by ¹H NMR, ¹³C NMR and mass spectral analysis.
Description
Keywords
Silica-sulfuric acid, Nitriles, Amides, Hydration
Citation
Chandrashekharappa, S. et al. 2016. Silica-sulfuric acid : novel, simple, efficient and reusable catalyst for hydration of nitrile to amide. Asian Journal of Chemistry. 28(10): 2177-2180.
DOI
https://doi.org/10.14233/ajchem.2016.19907